Description

2-(2,3-Difluorophenylmethoxy)Phenyl)Boronic Acid is a specialized organoboron compound, a key building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and inflammatory diseases.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as those used in OLEDs and sensors.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands and catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(2,3-Difluorophenylmethoxy)Phenyl)Boronic Acid
CAS No.	1256355-81-3
Molecular Formula	C13H11BF2O3
Molecular Weight	264.04 g/mol
Synonyms	[2-[(2,3-Difluorophenyl)methoxy]phenyl]boronic acid; 2-[(2,3-Difluorobenzyl)oxy]phenylboronic acid; (2-((2,3-Difluorobenzyl)oxy)phenyl)boronic acid; 2-(2,3-Difluorobenzyloxy)phenylboronic Acid; Boronic acid, B-[2-[(2,3-difluorophenyl)methoxy]phenyl]-; 1256355-81-3; 2-(2,3-Difluorobenzyloxy)benzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(2,3-Difluorophenylmethoxy)Phenyl)Boronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.