Description

(2,3-Difluorophenyl)Methoxyphenylboronic Acid CAS NO 1256355-76-6 is a specialized organoboron compound belonging to the arylboronic acid class, serving as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables efficient cross-coupling reactions, and the difluorophenyl and methoxyphenyl substituents impart unique electronic and steric properties to the final molecular architecture. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable components for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer Chemistry: Employed in the synthesis of functionalized polymers and dendrimers with specific thermal or optical properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new catalytic processes and material science applications.
• Custom Synthesis Services: Provided as a high-purity starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.

Basic Information

Item	Details
Product Name	(2,3-Difluorophenyl)Methoxyphenylboronic Acid
CAS No.	1256355-76-6
Molecular Formula	C13H11BF2O3
Molecular Weight	264.04 g/mol
Synonyms	[2,3-Difluorophenyl](4-Methoxyphenyl)boronic Acid; (4-Methoxyphenyl)-(2,3-difluorophenyl)boronic Acid; 2,3-Difluoro-4'-methoxy-[1,1'-biphenyl]-4-boronic Acid; 4-Methoxy-2',3'-difluorobiphenyl-4-boronic Acid; (2,3-Difluorophenyl)(4-methoxyphenyl)boronic acid; Boronic acid, B-(2,3-difluorophenyl)-4-methoxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Our production of (2,3-Difluorophenyl)Methoxyphenylboronic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure consistency and meet the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.