Description

5-Fluoro-2-(4-Fluorophenylmethoxy)Phenylboronic Acid is a high-purity, functionalized boronic acid derivative designed for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of potential active pharmaceutical ingredients (APIs), particularly those containing fluorinated biphenyl or diphenyl ether motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for catalysts or monomers for functional polymers.
• Chemical Biology Probes: Can be utilized to create tagged molecules for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Details
Product Name	5-Fluoro-2-(4-Fluorophenylmethoxy)Phenylboronic Acid
CAS No.	1256355-74-4
Molecular Formula	C13H11BF2O3
Molecular Weight	264.04 g/mol
Synonyms	5-Fluoro-2-[(4-fluorophenyl)methoxy]benzeneboronic acid; [5-Fluoro-2-[(4-fluorobenzyl)oxy]phenyl]boronic acid; 2-(4-Fluorobenzyloxy)-5-fluorophenylboronic acid; 5-Fluoro-2-(4-fluorobenzyloxy)phenylboronic acid; (5-Fluoro-2-{[(4-fluorophenyl)methyl]oxy}phenyl)boronic acid; Boronic acid, B-[5-fluoro-2-[(4-fluorophenyl)methoxy]phenyl]-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(4-Fluorophenylmethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.