Description

6-Chloropurine-13C2,15N is a stable isotope-labeled analog of 6-chloropurine, a key heterocyclic building block in organic synthesis. This compound is essential for advanced research and development, providing a critical tool for metabolic pathway tracing and pharmacokinetic studies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and analytical laboratories specializing in isotope dilution mass spectrometry and the synthesis of labeled nucleosides and nucleotides.

Application

• Isotope-Labeled Reference Standard: Used as an internal standard in LC-MS and GC-MS for the accurate quantification of purine derivatives in complex biological matrices.
• Tracer Studies: Enables detailed investigation of drug metabolism, absorption, and distribution pathways in preclinical research.
• Synthetic Intermediate: A crucial precursor for the synthesis of stable isotope-labeled adenine, guanine, and related nucleoside analogs.
• Mechanistic Research: Facilitates studies on enzyme mechanisms and nucleotide biosynthesis pathways in biochemical research.
• Pharmaceutical Development: Supports the development and validation of analytical methods for new drug candidates containing purine scaffolds.

Basic Information

Product Name	6-Chloropurine-13C2,15N
CAS No.	1246816-87-4
Molecular Formula	C313C2H3ClN315N
Molecular Weight	174.54 g/mol (approx.)
Synonyms	6-Chloro-9H-purine-13C2,15N; 6-Chloro-1H-purine-13C2,15N; 6-Chloro-7H-purine-13C2,15N; 6-Chloropurine-13C2,15N (Labeled); 6-Chloro-9H-purine-13C2,15N (Tautomer); 6-Chloro-1H-purine-13C2,15N (Tautomer); 6-Chloro-7H-purine-13C2,15N (Tautomer); 6-Chloro-3H-purine-13C2,15N (Tautomer)
EINECS	Contact for details

Quality Control

Our 6-Chloropurine-13C2,15N is manufactured under strict quality control protocols to ensure high isotopic and chemical purity. Each batch is analyzed using advanced techniques including NMR and Mass Spectrometry to confirm isotopic enrichment and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a desiccator or under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity	≥ 98 atom % 13C; ≥ 98 atom % 15N
Chemical Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.