Description

Methyl 4,5-Difluoro-2-Methylbenzoate is a high-purity fluorinated aromatic ester building block essential for advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the methyl ester group, which are critical for modulating the physicochemical properties of target molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working on novel active ingredients, particularly in the life sciences sector.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the difluoro motif can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Polymer Chemistry: Acts as a monomer or modifying agent for introducing fluorine into specialty polymers to improve chemical resistance and thermal stability.
• Organic Electronic Materials: Employed in the development of novel materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research: A versatile building block for Suzuki-Miyaura and other cross-coupling reactions to create complex, multi-substituted aromatic systems.

Basic Information

Product Name	Methyl 4,5-Difluoro-2-Methylbenzoate
CAS No.	1245515-60-9
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	4,5-Difluoro-2-methylbenzoic acid methyl ester; Methyl 4,5-difluoro-o-toluate; 2-Methyl-4,5-difluorobenzoic acid methyl ester; Benzoic acid, 4,5-difluoro-2-methyl-, methyl ester; Methyl 2-methyl-4,5-difluorobenzoate; 1245515-60-9; 4,5-Difluoro-2-methyl methyl benzoate
EINECS	Contact for details

Quality Control

Our Methyl 4,5-Difluoro-2-Methylbenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for traceability and to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.