Description

3-Fluoro-5-(Trifluoromethoxy)Benzoic Acid, 97% is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, makes it invaluable for modulating the lipophilicity, metabolic stability, and electronic properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, improving charge transport and thermal stability.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance and unique surface properties.
• Chemical Research & Development: A versatile reagent for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and the exploration of new chemical space.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethoxy)Benzoic Acid, 97%
CAS No.	1242258-49-6
Molecular Formula	C8H4F4O3
Molecular Weight	224.11 g/mol
Synonyms	3-Fluoro-5-(trifluoromethoxy)benzoic acid; Benzoic acid, 3-fluoro-5-(trifluoromethoxy)-; 1242258-49-6; 5-(Trifluoromethoxy)-3-fluorobenzoic acid; 3-Fluoro-5-trifluoromethoxybenzoic acid; α-Fluoro-α'-(trifluoromethoxy)isophthalic acid (related); F-TFMBA (abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethoxy)Benzoic Acid, 97% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The compound may be hygroscopic; handle and store under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.