Description

4-Fluoro-2-(Trifluoromethoxy)Benzoic Acid, 97% is a high-purity fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique trifluoromethoxy and fluorine substituents, which are essential for modulating the physicochemical and biological properties of target molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance lipophilicity, metabolic stability, and biological activity.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs) due to its ability to influence dielectric anisotropy and rotational viscosity.
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Organic Electronic Materials: Utilized in the synthesis of materials for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs) to fine-tune electron affinity and energy levels.
• Chemical Research & Development: Employed as a versatile fluorinated scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethoxy)Benzoic Acid, 97%
CAS No.	1242250-37-8
Molecular Formula	C8H4F4O3
Molecular Weight	224.11 g/mol
Synonyms	4-Fluoro-2-(trifluoromethoxy)benzoic acid; 2-(Trifluoromethoxy)-4-fluorobenzoic acid; Benzoic acid, 4-fluoro-2-(trifluoromethoxy)-; 4-Fluoro-α,α,α-trifluoro-o-anisic acid; 4-Fluoro-2-trifluoromethoxybenzoic acid; F-TFMBA; 4F-2-TFMOBA; 1242250-37-8
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethoxy)Benzoic Acid, 97% is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the specified grade and consistency for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support custom purity requirements to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.