Description

9,15-Dioxo-11Alpha-Hydroxy-2,3,4,5-Tetranor-Prostan-1,20-Dioic-17,17,18,18,19,19-D6 Acid is a high-purity, deuterium-labeled prostanoid derivative, serving as a critical analytical standard and synthetic intermediate. Its primary value lies in enabling precise quantification and metabolic pathway tracing in advanced pharmaceutical research and development. This compound is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and contract research sectors, particularly those focused on prostaglandin-related drug discovery, bioanalytical method development, and stable isotope labeling studies.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the accurate quantification of prostaglandin metabolites and related eicosanoids in complex biological matrices.
• Pharmaceutical R&D: Serves as a key intermediate or reference compound in the synthesis and development of novel therapeutics targeting inflammatory pathways.
• Metabolic Studies: Facilitates tracer studies to investigate the metabolism, pharmacokinetics, and biochemical fate of prostanoids in vivo.
• Biomarker Research: Employed in clinical and preclinical research to develop and validate assays for oxidative stress and inflammation biomarkers.
• Quality Control Reference: Provides a certified reference material for ensuring the accuracy and consistency of analytical methods in QC laboratories.
• Stable Isotope Labeling: Acts as a source of deuterium label for synthesizing other isotopically labeled compounds for mass spectrometry applications.

Basic Information

Item	Details
Product Name	9,15-Dioxo-11Alpha-Hydroxy-2,3,4,5-Tetranor-Prostan-1,20-Dioic-17,17,18,18,19,19-D6 Acid
CAS No.	1240398-16-6
Molecular Formula	C16H16D6O6
Molecular Weight	304.35 g/mol (approx.)
Synonyms	11α-Hydroxy-9,15-dioxo-2,3,4,5-tetranorprostan-1,20-dioic-17,17,18,18,19,19-d6 acid; Deuterated Tetranor Prostaglandin Metabolite; 11α-OH-9,15-diketo-13,14-dihydro-2,3,4,5-tetranor-PGF2α-1,20-dioic-d6 acid; 9,15-Dioxo-11α-hydroxy-2,3,4,5-tetranor-prostanoic-17,17,18,18,19,19-d6 acid; PGDM-d6; d6-9,15-Dioxo-11α-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid; Tetranor PGDM-d6; 11α-Hydroxy-9,15-dioxo-2,3,4,5-tetranorprost-13-en-1,20-dioic-d6 acid
EINECS	Contact for details

Quality Control

Every batch of 9,15-Dioxo-11Alpha-Hydroxy-2,3,4,5-Tetranor-Prostan-1,20-Dioic-17,17,18,18,19,19-D6 Acid is manufactured and analyzed under strict quality systems. We employ advanced analytical techniques including NMR, HPLC, and mass spectrometry to ensure high chemical purity, isotopic enrichment, and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, isotopic purity (D-enrichment), and related substance profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Chemical Purity (NMR)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.