Description

2-Fluoro-4-(pentafluorosulfur)benzoic acid is a high-value, fluorinated aromatic building block characterized by its unique combination of a benzoic acid core with fluorine and a pentafluorosulfanyl (SF5) substituent. This structure is critical for modifying the physicochemical properties of advanced molecules, particularly enhancing their metabolic stability, lipophilicity, and overall bioactivity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as by material scientists exploring advanced polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the pentafluorosulfanyl group into drug candidates, aiming to improve potency and pharmacokinetic profiles.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the SF5 group can contribute to enhanced efficacy and environmental persistence.
• Material Science: Serves as a monomer or precursor for specialty polymers, coatings, and liquid crystals with unique dielectric and surface properties.
• Chemical Synthesis: Employed as a versatile building block in organic chemistry for creating complex fluorinated compounds for various research applications.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands in coordination chemistry and catalysis, leveraging the electron-withdrawing nature of the SF5 group.

Basic Information

Product Name	2-Fluoro-4-(pentafluorosulfur)benzoic Acid
CAS No.	1240257-03-7
Molecular Formula	C7H2F6O2S
Molecular Weight	264.15 g/mol
Synonyms	4-(Pentafluoro-λ6-sulfanyl)-2-fluorobenzoic acid; 2-Fluoro-4-(pentafluorosulfanyl)benzoic acid; Benzoic acid, 2-fluoro-4-(pentafluorosulfanyl)-; SF5-Benzoic Acid derivative; 2-F-4-SF5-BA
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(pentafluorosulfur)benzoic acid is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our standard grade typically meets a high purity specification, verified by advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.