Description

Tenofovir (Maleate) CAS NO 1236287-04-9 is the maleate salt form of Tenofovir, a potent nucleotide reverse transcriptase inhibitor (NRTI). This specific salt form is crucial for enhancing the stability and bioavailability of the active pharmaceutical ingredient (API) in final drug formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antiviral medications.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of antiviral drugs, particularly for HIV-1 and Hepatitis B treatment.
• Pharmaceutical Intermediates for synthesizing more complex prodrug forms like Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF).
• Reference Standard in analytical laboratories for quality control and method validation of antiviral products.
• Biomedical Research as a key compound for studying nucleotide analog mechanisms and developing new antiviral therapies.
• Formulation Development for creating stable solid dosage forms such as tablets and capsules.

Basic Information

Product Name	Tenofovir (Maleate)
CAS No.	1236287-04-9
Molecular Formula	C14H22N5O8P
Molecular Weight	419.33 g/mol
Synonyms	Tenofovir Maleate; (R)-PMPA Maleate; 9-[(R)-2-[[Bis[[(isopropoxycarbonyl)oxy]methoxy]phosphinyl]methoxy]propyl]adenine Maleate; GS 1278 Maleate; PMPA Maleate; Bis(POC)PMPA Maleate; Viread precursor salt
EINECS	Contact for details

Quality Control

Our Tenofovir (Maleate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment. We can support development with material compliant to various pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.