Description

Diethyl Rivastigmine CAS NO 1230021-34-7 is a key pharmaceutical intermediate and a structural analog of Rivastigmine, a well-established acetylcholinesterase inhibitor. This compound is of critical importance for the research, development, and production of advanced treatments targeting neurodegenerative disorders. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers engaged in the synthesis of active pharmaceutical ingredients (APIs) for cognitive enhancement therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Rivastigmine and its derivative compounds.
• Active Pharmaceutical Ingredient (API) Research: Used in the development and scale-up of new acetylcholinesterase inhibitor formulations.
• Neurological Disorder Therapeutics: Serves as a key material in the production of medications for Alzheimer's disease and dementia.
• Chemical Reference Standard: Employed as a high-purity standard in analytical testing and quality control laboratories.
• Process Chemistry & Optimization: Utilized in route scouting and process development for more efficient API manufacturing.
• Academic & Institutional Research: Supports pharmacological studies investigating cholinergic system modulation.

Basic Information

Product Name	Diethyl Rivastigmine
CAS No.	1230021-34-7
Molecular Formula	C14H22N2O2
Molecular Weight	250.34 g/mol
Synonyms	(S)-3-[1-(Dimethylamino)ethyl]phenyl diethylcarbamate; Diethyl (3-[(1S)-1-(dimethylamino)ethyl]phenyl) carbamate; Rivastigmine Diethyl Analog; Rivastigmine Impurity; ENA 713 Diethyl Derivative; N-Ethyl-N-methylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester (diethyl analog)
EINECS	Contact for details

Quality Control

Our Diethyl Rivastigmine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific customer or regulatory standards (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.