Description

S-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-5,5',6,6',7,7',8,8'-Octahydro-[1,1'-Binaphthalene]-2,2'-Diol is a high-value, chiral binaphthol derivative characterized by its unique octahydro structure and peripheral trifluoromethylphenyl groups. This compound matters as a sophisticated ligand precursor and chiral building block for asymmetric synthesis, offering significant potential to influence stereoselectivity in catalytic reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• As a chiral ligand or ligand precursor in asymmetric metal-catalyzed reactions (e.g., hydrogenation, coupling).
• As a key intermediate in pharmaceutical research for the development of new therapeutic agents.
• As a building block for chiral catalysts used in fine chemical and agrochemical synthesis.
• In the research and development of advanced organic electronic materials and liquid crystals.
• For the synthesis of chiral stationary phases (CSPs) or selectors for analytical and preparative chromatography.
• In academic and industrial research exploring novel supramolecular structures and host-guest chemistry.

Basic Information

Item	Details
Product Name	S-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-5,5',6,6',7,7',8,8'-Octahydro-[1,1'-Binaphthalene]-2,2'-Diol
CAS No.	1228600-98-3
Molecular Formula	C38H30F6O2
Molecular Weight	632.64 g/mol
Synonyms	(S)-H8-BINOL-3,3'-bis(4-(trifluoromethyl)phenyl); (S)-Octahydro-3,3'-bis[4-(trifluoromethyl)phenyl]-1,1'-binaphthyl-2,2'-diol; (S)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-bis[4-(trifluoromethyl)phenyl]-[1,1'-binaphthalene]-2,2'-diol; S-3,3'-Di(4-trifluoromethylphenyl)-H8-BINOL; Chiral Octahydro Binaphthol Derivative; (S)-H8-3,3'-(4-CF3-Ph)2-BINOL
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, chiral HPLC, 1H/19F/13C NMR, and mass spectrometry to confirm identity, enantiomeric excess (ee), and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a cGMP-compliant quality management system for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a desiccator or under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.