Description

3-Bromo-2-(Trifluoromethyl)Benzoic Acid is a high-purity, multifunctional aromatic building block characterized by its bromine and trifluoromethyl substituents, which are critical for modulating electronic properties and lipophilicity in advanced molecular structures. This compound is essential for research and development chemists requiring precise, reliable intermediates to accelerate innovation in life sciences and material chemistry. It is primarily utilized in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials where its unique halogenated and fluorinated motif introduces valuable bioactivity and stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for oncology, CNS, and anti-inflammatory targets.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a functional monomer to impart specific properties like chemical resistance or altered refractive index in specialty polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A versatile building block for exploring new chemical spaces in academic and industrial R&D laboratories.

Basic Information

Product Name	3-Bromo-2-(Trifluoromethyl)Benzoic Acid
CAS No.	1227605-02-8
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	2-(Trifluoromethyl)-3-bromobenzoic acid; 3-Bromo-α,α,α-trifluoro-o-toluic acid; Benzoic acid, 3-bromo-2-(trifluoromethyl)-; 3-Bromo-2-trifluoromethylbenzoic acid; 3-Bromo-α,α,α-trifluoro-2-methylbenzoic acid
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-2-(Trifluoromethyl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.