Description

3-(2-Fluoro-Phenyl)-Dihydro-Furan-2,5-Dione is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique structural motif, which serves as a versatile precursor for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with specific electronic or optical properties.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the incorporation of a fluorinated dihydrofuranone scaffold.

Basic Information

Product Name	3-(2-Fluoro-Phenyl)-Dihydro-Furan-2,5-Dione
CAS No.	1226148-99-7
Molecular Formula	C10H7FO3
Molecular Weight	194.16 g/mol
Synonyms	3-(2-Fluorophenyl)dihydrofuran-2,5-dione; 2-(2-Fluorobenzoyl)acetic acid, lactone; 3-(2-Fluorophenyl)-2,5-dihydrofuran-2,5-dione; 2,5-Dihydro-3-(2-fluorophenyl)furan-2,5-dione; 2-(2-Fluorobenzoyl)acetic acid γ-lactone; 3-(o-Fluorophenyl)dihydrofuran-2,5-dione; Fluorinated succinic anhydride derivative
EINECS	Contact for details

Quality Control

Our production of 3-(2-Fluoro-Phenyl)-Dihydro-Furan-2,5-Dione adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and scale-up projects with material that meets the exacting requirements for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.