Description

Abt-450 is a high-purity, non-nucleoside chemical compound identified by CAS NO 1221573-85-8. This specialized intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors seeking reliable, high-quality building blocks for complex molecular synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Biochemical Research: Used in life science research for studying biological pathways and developing assay protocols.
• Organic Synthesis: Employed as a versatile intermediate in complex multi-step organic reactions to create novel chemical entities.
• Preclinical Development: Essential for producing compounds used in pharmacological and toxicological studies during drug discovery.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	Abt-450
CAS No.	1221573-85-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ABT-450; 1221573-85-8; Paritaprevir intermediate; ABT 450; ABT450; HCV NS3/4A protease inhibitor intermediate; 4H-Cyclopenta[b]thiophene-4-one, 2-[(2S)-1-[(2S)-2-[[(2S,5S)-1-(2-methylpropanoyl)-5-phenyl-4,5-dihydro-1H-pyrrol-2-yl]carbonyl]amino]-5-azaspiro[2.4]hept-5-yl]-3-(2-methylpropyl)-1,1-dioxo-
EINECS	Contact for details

Quality Control

Our Abt-450 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.