Description

Methyl 4-Benzyloxy-2-Fluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis and pharmaceutical research. Its core value lies in providing a versatile, protected intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and benzyl-protected phenol functionalities into target structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and other transformations to create complex, functionalized biphenyl and heterocyclic systems.
• Protecting Group Chemistry: The benzyloxy group acts as a protective group for phenols, which can be selectively removed in multi-step synthetic sequences.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Methyl 4-Benzyloxy-2-Fluorobenzoate
CAS No.	1221179-04-9
Molecular Formula	C15H13FO3
Molecular Weight	260.26 g/mol
Synonyms	4-(Benzyloxy)-2-fluorobenzoic Acid Methyl Ester; Methyl 4-(Benzyloxy)-2-fluorobenzoate; 2-Fluoro-4-(phenylmethoxy)benzoic Acid Methyl Ester; Benzoic acid, 4-(benzyloxy)-2-fluoro-, methyl ester; Methyl 2-fluoro-4-(phenylmethoxy)benzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Benzyloxy-2-Fluorobenzoate is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC Area %)	≥99.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.