Description

2-Amino-4,6-Dimethoxypyrimidine-D6 is a deuterated isotopologue of a key pyrimidine derivative, serving as a crucial building block and analytical standard in advanced chemical synthesis. Its primary value lies in enabling precise metabolic and pharmacokinetic studies through the use of stable isotope-labeled compounds. This high-purity material is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing and analyzing novel active ingredients.

Application

• Pharmaceutical Research & Development: As a stable isotope-labeled internal standard for the accurate quantification of its non-deuterated counterpart in bioanalytical methods like LC-MS/MS.
• Metabolic Pathway Tracing: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of active pharmaceutical ingredients in biological systems.
• Chemical Synthesis Intermediate: A deuterated building block for the synthesis of more complex labeled compounds, such as deuterated herbicides or pharmaceuticals.
• Agrochemical Development: Employed in the research of novel pyrimidine-based herbicides and fungicides, utilizing the deuterium label for mechanistic studies.
• Analytical Reference Standard: Provides a critical reference material for method development and validation in quality control laboratories to ensure specificity and accuracy.

Basic Information

Product Name	2-Amino-4,6-Dimethoxypyrimidine-D6
CAS No.	1219803-92-5
Molecular Formula	C6H3D6N3O2
Molecular Weight	172.22 g/mol
Synonyms	2-Amino-4,6-dimethoxypyrimidine-d6; 4,6-Dimethoxy-2-pyrimidinamine-d6; 2-Pyrimidinamine, 4,6-dimethoxy-, d6-; Deuterated 2-Amino-4,6-dimethoxypyrimidine; (Dimethoxy-d6)-2-aminopyrimidine; Perdeuterated 2-Amino-4,6-dimethoxypyrimidine; 2-ADMP-d6; A-4,6-DMP-d6
EINECS	Contact for details

Quality Control

Our 2-Amino-4,6-Dimethoxypyrimidine-D6 is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-content), chemical purity, and identity confirmation. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.