Description

Faldaprevir is a potent and selective inhibitor of the hepatitis C virus (HCV) NS3/4A protease, a key enzyme in the viral replication cycle. This high-purity intermediate is critical for the research and development of next-generation antiviral therapies targeting chronic HCV infection. It is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and API manufacturers focused on antiviral drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of antiviral active pharmaceutical ingredients (APIs).
• Antiviral Research: Critical reference standard and starting material for the discovery and development of novel HCV protease inhibitors.
• Biochemical Studies: Used in enzymatic assays to study the inhibition kinetics and mechanism of action against the HCV NS3/4A protease.
• Process Development: Serves as a benchmark compound for optimizing synthetic routes, scaling up production, and ensuring quality control in API manufacturing.
• Academic Research: Utilized in university and institutional labs for virology and medicinal chemistry research programs.

Basic Information

Product Name	Faldaprevir
CAS No.	1219105-46-0
Molecular Formula	C₃₅H₄₅F₃N₆O₉S
Molecular Weight	782.83 g/mol
Synonyms	BI 201335; BI-201335; BILN 2061 analog; (1R,3aR,6aS)-2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylsulfonylcarbamoyl)-2,2-dimethylpropyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide; 1H-Cyclopenta[c]pyrrole-3-carboxamide, 2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(2-pyrazinylcarbonyl)amino]acetyl]amino]-3,3-dimethyl-1-oxobutyl]-N-[(3S)-2,2-dimethyl-1-[(sulfamoylcyclopropyl)amino]-1-oxopropan-2-yl]octahydro-, (1R,3aS,6aS)-
EINECS	Contact for details

Quality Control

Our Faldaprevir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) documenting full specifications are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Chiral Purity	≥99.0% ee

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.