Description

(R)-n-(2-Pyridyl) tert-Butanesulfinamide CAS NO 1217899-34-7 is a high-purity chiral sulfinamide building block, a critical reagent in asymmetric synthesis. Its primary value lies in its role as a highly effective chiral auxiliary and ligand for the stereoselective construction of nitrogen-containing compounds, particularly amines. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create enantiomerically pure active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Asymmetric Synthesis of Chiral Amines: Serves as a key chiral auxiliary in nucleophilic addition reactions to N-sulfinyl imines for the production of enantiomerically enriched amines.
• Pharmaceutical Intermediate Manufacturing: Used in the R&D and scale-up synthesis of complex drug candidates, especially those requiring specific stereochemistry at nitrogen centers.
• Ligand for Catalysis: Can be utilized as a precursor or component in chiral ligand systems for transition metal-catalyzed asymmetric transformations.
• Agrochemical Research: Applied in the synthesis of chiral amine-based herbicides, fungicides, and plant growth regulators.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and for studying stereoselective reaction mechanisms.
• Fine Chemical Production: Enables the manufacture of high-value, specialty chemicals with defined stereochemistry for various advanced material applications.

Basic Information

Product Name	(R)-n-(2-Pyridyl) tert-Butanesulfinamide
CAS No.	1217899-34-7
Molecular Formula	C9H14N2OS
Molecular Weight	198.28 g/mol
Synonyms	(R)-2-Pyridyl tert-Butanesulfinamide; (R)-N-(Pyridin-2-yl)-2-methylpropane-2-sulfinamide; (R)-tert-Butanesulfinamide, N-2-pyridinyl-; (R)-N-(2-Pyridinyl)-2-methyl-2-propanesulfinamide; (R)-2-Methyl-N-(pyridin-2-yl)propane-2-sulfinamide; (R)-p-Toluenesulfinamide, N-2-pyridinyl- (common misnomer); (R)-2-Pyridinesulfinamide, N-tert-butyl-; (R)-N-(2-Pyridyl)-tert-butylsulfinamide
EINECS	Contact for details

Quality Control

Every batch of (R)-n-(2-Pyridyl) tert-Butanesulfinamide is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity consistent with research and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.