Description

(+/-)-Epicatechin -[13C3] is a stable isotope-labeled analog of the natural flavonoid epicatechin, where three carbon atoms are replaced with the carbon-13 isotope. This compound is essential for use as an internal standard in quantitative mass spectrometry, enabling precise and accurate measurement of epicatechin levels in complex biological matrices. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and food science industries who require definitive analytical data for pharmacokinetic studies, metabolic research, and product standardization.

Application

• Quantitative Mass Spectrometry (MS) Internal Standard: Primary use for accurate quantification of native epicatechin in LC-MS/MS and GC-MS applications.
• Pharmacokinetic and Drug Metabolism Studies: Tracing the absorption, distribution, metabolism, and excretion (ADME) of epicatechin in preclinical and clinical research.
• Biomarker Analysis and Clinical Research: Used in assays to measure epicatechin as a dietary biomarker or therapeutic agent in human plasma, serum, and urine.
• Nutraceutical and Dietary Supplement Analysis: Ensuring label claim accuracy and batch-to-batch consistency in products containing epicatechin or cocoa extracts.
• Food and Beverage Science: Quantifying epicatechin content in chocolate, tea, wine, and other flavonoid-rich products for quality control and nutritional labeling.
• Stable Isotope Dilution Assay (SIDA): Serving as the labeled spike in highly precise analytical methods to correct for sample preparation losses and matrix effects.

Basic Information

Product Name	(+/-)-Epicatechin -[13C3]
CAS No.	1217780-28-3
Molecular Formula	C1513C3H14O6
Molecular Weight	~ 293.25 g/mol
Synonyms	(±)-Epicatechin-13C3; Epicatechin (13C3); 2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol-13C3; 3,3',4',5,7-Pentahydroxyflavan-13C3; (-)-Epicatechin-13C3; (+)-Epicatechin-13C3; EC-13C3; Isotopically Labeled Epicatechin
EINECS	Contact for details

Quality Control

Every batch of (+/-)-Epicatechin -[13C3] is manufactured and analyzed under strict quality protocols to ensure the highest isotopic and chemical purity for demanding analytical applications. Our quality commitment includes comprehensive testing via NMR, HPLC, and mass spectrometry to verify isotopic enrichment, chemical identity, and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data including assay, isotopic purity, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99 atom % 13C
Isotopic Enrichment	≥ 99% 13C3
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.