Description

Ent-Calindol Amide-13C is a stable isotope-labeled analog of a key pharmaceutical intermediate, where a carbon-13 atom is incorporated into its molecular structure. This precise labeling is critical for advanced analytical applications, providing an internal standard for accurate quantification and metabolic pathway elucidation. It is primarily required by research institutions, pharmaceutical developers, and CROs engaged in drug discovery, pharmacokinetic studies, and high-precision mass spectrometry.

Application

• Internal standard for the quantitative analysis of Calindol and related compounds using LC-MS/MS and GC-MS.
• Tracer compound in drug metabolism and pharmacokinetics (DMPK) studies to investigate absorption, distribution, metabolism, and excretion (ADME).
• Critical reagent in the synthesis and quality control of isotopically labeled active pharmaceutical ingredients (APIs).
• Use in biomedical research for mechanistic studies involving calcium-sensing receptor (CaSR) modulators.
• Reference material for calibrating analytical instruments in regulatory bioanalysis.

Basic Information

Product Name	Ent-Calindol Amide-13C
CAS No.	1217724-96-3
Molecular Formula	C21H2613CN3O2
Molecular Weight	Contact for details
Synonyms	(1R)-1-(3-Chlorophenyl)-3-[(1R)-1-(methylamino)ethyl]-1H-indole-2-carboxamide-13C; Calindol Amide-13C (ent-form); (R)-1-(3-Chlorophenyl)-3-((R)-1-(methylamino)ethyl)-1H-indole-2-carboxamide-13C; Carbon-13 labeled Calindol Amide enantiomer; Stable Isotope Labeled CaSR Ligand; [13C]-Ent-Calindol Amide
EINECS	Contact for details

Quality Control

Our Ent-Calindol Amide-13C is manufactured under strict quality systems to ensure high isotopic and chemical purity suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to cGMP principles for research-grade materials, ensuring traceability, consistency, and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (by HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.