Description

3-Fluoro-5-Morpholinophenylboronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its molecular structure, featuring both a morpholine ring and a boronic acid group, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal reagent for forming carbon-carbon bonds between aryl halides and this boronic acid, crucial for synthesizing biaryl structures found in many pharmaceuticals.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of new drug candidates, particularly those targeting the central nervous system (CNS) and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic components.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and other fluorophore systems.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of enzyme inhibitors or activity-based probes due to its reactive boronic acid group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Item	Details
Product Name	3-Fluoro-5-Morpholinophenylboronic Acid
CAS No.	1217500-95-2
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	(3-Fluoro-5-morpholinophenyl)boronic acid; 3-Fluoro-5-morpholinebenzeneboronic acid; 5-Morpholino-3-fluorophenylboronic acid; Boronic acid, B-(3-fluoro-5-morpholinophenyl)-; 1217500-95-2; 3-Fluoro-5-morpholinobenzene-1-boronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Morpholinophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.