Description

3,4-Difluoro-5-(Methoxycarbonyl)Phenylboronic Acid is a high-purity, multifunctional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in its role as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and fluorinated pharmaceutical development.
• Agrochemical Synthesis: Used to create advanced, fluorinated active ingredients for crop protection products, enhancing their stability and biological activity.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Functional Material Precursor: Employed in the production of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents due to its reactive boronic acid handle.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses and CROs (Contract Research Organizations) serving the global life sciences industry.

Basic Information

Product Name	3,4-Difluoro-5-(Methoxycarbonyl)Phenylboronic Acid
CAS No.	1217500-74-7
Molecular Formula	C9H7BF2O4
Molecular Weight	228.96 g/mol
Synonyms	(3,4-Difluoro-5-(methoxycarbonyl)phenyl)boronic acid; 5-Borono-3,4-difluorobenzoic acid methyl ester; Methyl 3,4-difluoro-5-boronobenzoate; 3,4-Difluoro-5-(methoxycarbonyl)benzeneboronic acid; Methyl 5-borono-3,4-difluorobenzoate; 3,4-Difluoro-5-(carbomethoxy)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-5-(Methoxycarbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and moisture, the container must be kept sealed and handled under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.