Description

3-Fluoro-5-(Hydrazinecarbonyl)Phenylboronic Acid is a multifunctional boronic acid derivative that serves as a valuable bifunctional building block in modern synthetic chemistry. Its unique structure, combining a boronic acid group for Suzuki-Miyaura cross-coupling with a reactive hydrazinecarbonyl moiety, enables the efficient construction of complex molecular architectures. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology, via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its boronic acid functionality allows for the introduction of aromatic segments.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, where precise molecular structure is critical.
• Bioconjugation and Probe Synthesis: The reactive hydrazide group facilitates conjugation to biomolecules (proteins, antibodies) for creating diagnostic probes and targeted delivery systems.
• Chemical Biology Tool: Utilized in the synthesis of activity-based probes (ABPs) and other chemical tools for studying enzyme function and biological pathways.

Basic Information

Product Name	3-Fluoro-5-(Hydrazinecarbonyl)Phenylboronic Acid
CAS No.	1217500-73-6
Molecular Formula	C7H8BFN2O3
Molecular Weight	197.96 g/mol
Synonyms	(3-Fluoro-5-(hydrazinecarbonyl)phenyl)boronic acid; 3-Carbamoyl-5-fluorobenzeneboronic acid hydrazide; 5-Borono-3-fluorobenzoic acid hydrazide; 3-Fluoro-5-(hydrazinylformyl)phenylboronic acid; B-(3-Fluoro-5-hydrozinocarbonylphenyl)boronic acid; 1217500-73-6; Boronic acid, B-[3-fluoro-5-(hydrazinocarbonyl)phenyl]-; 3-Fluoro-5-hydrazinylcarbonylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-(Hydrazinecarbonyl)Phenylboronic Acid is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical synthesis workflows. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.