Description

2-Fluoro-3-Isobutoxyphenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to construct complex heterocyclic structures found in advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke organic compounds for clients.

Basic Information

Product Name	2-Fluoro-3-Isobutoxyphenylboronic Acid
CAS No.	1217500-66-7
Molecular Formula	C10H14BFO3
Molecular Weight	212.03 g/mol
Synonyms	(2-Fluoro-3-isobutoxyphenyl)boronic Acid; 2-Fluoro-3-isobutoxybenzeneboronic Acid; Boronic acid, B-(2-fluoro-3-isobutoxyphenyl)-; 1217500-66-7; 2-Fluoro-3-(2-methylpropoxy)phenylboronic Acid; 3-Isobutoxy-2-fluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Isobutoxyphenylboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.