Description

3-Amino-1,4-Dimethyl-5H-Pyrido[4,3-B]Indole-13C2,15N Acetate is a high-purity, isotopically labeled heterocyclic compound, specifically designed for advanced analytical and research applications. Its core value lies in its use as a critical internal standard and tracer in mass spectrometry, enabling precise quantification and metabolic pathway elucidation. This product is essential for researchers and quality control laboratories in the pharmaceutical, contract research organization (CRO), and forensic toxicology sectors who require definitive, interference-free analytical data.

Application

• Mass Spectrometry Internal Standard: Used as a stable isotope-labeled internal standard (SIL-IS) for the accurate quantification of its unlabeled counterpart or related metabolites in complex biological matrices via LC-MS/MS and GC-MS.
• Metabolic Studies & Pharmacokinetics: Employed as a tracer to study the absorption, distribution, metabolism, and excretion (ADME) profiles of heterocyclic amine compounds in preclinical and clinical research.
• Biomarker Research: Facilitates the discovery and validation of specific biomarkers related to exposure or disease states in proteomic and metabolomic investigations.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradants during drug development and stability testing.
• Forensic & Clinical Toxicology: Serves as a reference material for the confirmatory analysis of specific compounds in forensic and clinical toxicology screenings.
• Environmental Analysis: Applied in trace-level detection and quantification studies of related environmental contaminants.

Basic Information

Product Name	3-Amino-1,4-Dimethyl-5H-Pyrido[4,3-B]Indole-13C2,15N Acetate
CAS No.	1217002-93-1
Molecular Formula	C15H1513C215N N2O2 * (CH3COOH)
Molecular Weight	Contact for details
Synonyms	3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole-13C2,15N acetate salt; Trp-P-2-13C2,15N acetate; 3-Amino-1-methyl-5H-pyrido[4,3-b]indole-13C2,15N acetate (common naming variant); 1,4-Dimethyl-3-amino-5H-pyrido[4,3-b]indole-13C2,15N acetate; Isotopically labeled Trp-P-2 acetate; [13C2,15N]-3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole acetate; 13C2,15N-labeled heterocyclic amine standard; 13C2,15N-AcTrp-P-2
EINECS	Contact for details

Quality Control

Every batch of our isotopically labeled compounds is produced and analyzed under strict quality management to ensure identity, purity, and isotopic enrichment meet the exacting standards required for analytical research. Our standard specifications include verification by NMR (1H, 13C), mass spectrometry, and HPLC for chemical and isotopic purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results, including isotopic purity (atom % 13C and 15N), is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light brown solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Chemical Purity)
Isotopic Purity (MS)	≥ 98 atom % 13C; ≥ 98 atom % 15N
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.