Description

2-(2,6-Difluoro-Phenyl)-2-Methyl-Propionic Acid is a high-purity fluorinated organic acid building block of significant importance in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its difluorophenyl moiety imparts desirable metabolic stability and bioavailability. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in cutting-edge R&D and production.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery and development, particularly for anti-inflammatory and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with unique thermal and chemical resistance properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other catalytic processes to introduce the valuable 2,6-difluorophenyl group into target molecules.
• Chemical Research: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-(2,6-Difluoro-Phenyl)-2-Methyl-Propionic Acid
CAS No.	1216838-87-7
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2-Methyl-2-(2,6-difluorophenyl)propanoic Acid; α,α-Dimethyl-2,6-difluorobenzeneacetic Acid; 2,6-Difluoro-α,α-dimethylbenzeneacetic Acid; 2-(2,6-Difluorophenyl)-2-methylpropanoic Acid; 2,6-Difluoro-α-methylhydrocinnamic Acid (related); Diflurophenyl Methyl Propionic Acid; DFMPA (abbreviation); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-(2,6-Difluoro-Phenyl)-2-Methyl-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.