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2-Aminodipyrido[1,2-A:3',2-D]Imidazole-13C3 Hydrochloride CAS NO 1216562-43-4
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CAS No.:1216562-43-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Aminodipyrido[1,2-A:3',2-D]Imidazole-13C3 Hydrochloride is a stable isotope-labeled analog of a heterocyclic amine, specifically labeled with three carbon-13 atoms. This compound is of critical importance for use as an internal standard in advanced analytical techniques, enabling highly accurate quantification and reliable trace analysis. It is primarily needed by researchers and quality control laboratories in the pharmaceutical, environmental, and forensic toxicology sectors for method development and validation.
Application
- Internal Standard for Mass Spectrometry (MS): Essential for precise quantification in LC-MS/MS and GC-MS analysis, correcting for instrument variability and matrix effects.
- Metabolic and Pharmacokinetic Studies: Used in ADME (Absorption, Distribution, Metabolism, Excretion) research to track the fate of the parent compound in biological systems.
- Toxicological and Environmental Analysis: Enables accurate detection and measurement of heterocyclic aromatic amines (HAAs) or their metabolites in complex samples like food, urine, or environmental matrices.
- Pharmaceutical Impurity Profiling: Supports the identification and quantification of genotoxic impurities or degradation products in active pharmaceutical ingredients (APIs).
- Biomarker Research: Facilitates the study of DNA adducts formed by related compounds, serving as a key tool in cancer research and mechanistic toxicology.
- Method Development and Validation: Provides a critical reference point for developing robust, sensitive, and specific analytical methods compliant with ICH and FDA guidelines.
Basic Information
| Product Name | 2-Aminodipyrido[1,2-A:3',2-D]Imidazole-13C3 Hydrochloride |
| CAS No. | 1216562-43-4 |
| Molecular Formula | C913C3H9N5•HCl |
| Molecular Weight | Contact for details |
| Synonyms | 2-Amino-13C3-dipyrido[1,2-a:3',2'-d]imidazole Hydrochloride; 2-Amino-13C3-DIP Imidazole HCl; 2-Amino-13C3-1,2,4-Triazolo[4,3-a]pyrido[3,2-e]pyrazine Hydrochloride; 13C3-Labeled 2-Aminodipyridoimidazole HCl; Isotope-labeled HAA Standard; [13C3]-2-ADIP HCl; 2-ADIP-13C3 Hydrochloride; Carbon-13 Labeled Heterocyclic Amine Internal Standard |
| EINECS | Contact for details |
Quality Control
Every batch of 2-Aminodipyrido[1,2-A:3',2-D]Imidazole-13C3 Hydrochloride is produced and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity verified by advanced spectroscopic and chromatographic methods, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and analytical data is provided with each shipment to ensure traceability and support your regulatory compliance.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity. For long-term storage, consider storing at 2-8°C.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to expected mass spectrum |
| Purity (HPLC) | ≥ 98.0% |
| Isotopic Enrichment | ≥ 99 atom % 13C |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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