Description

2-Fluoro-6-Methylbiphenyl-3-Carboxylic Acid is a high-purity fluorinated biphenyl derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a carboxylic acid functional group with fluorine and methyl substituents on a biphenyl scaffold, enabling precise modifications in target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials that require fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-Fluoro-6-Methylbiphenyl-3-Carboxylic Acid
CAS No.	1215206-80-6
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	2'-Fluoro-6'-methyl-[1,1'-biphenyl]-3-carboxylic acid; 3-Biphenylcarboxylic acid, 2-fluoro-6-methyl-; 2-Fluoro-6-methylbiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 2'-fluoro-6'-methyl-; 2-Fluoro-6-methyl-3-phenylbenzoic acid
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-6-Methylbiphenyl-3-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.