Description

Methyl 3-Fluoro-4-(Methylsulfonyl)Benzoate is a high-purity, fluorinated aromatic ester derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable building block for introducing both fluorine and methylsulfonyl functional groups into target structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the bioactivity-enhancing properties of the fluorine atom.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced materials with specific electronic or surface properties.
• Ligand and Catalyst Development: Employed in the creation of complex ligands for catalysis and molecular recognition applications.
• Chemical Biology Probes: Utilized as a starting material for synthesizing fluorescent tags or activity-based probes for biological research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Methyl 3-Fluoro-4-(Methylsulfonyl)Benzoate
CAS No.	1215074-49-9
Molecular Formula	C9H9FO4S
Molecular Weight	232.23 g/mol
Synonyms	Methyl 3-Fluoro-4-(Methylsulfonyl)Benzoate; Benzoic acid, 3-fluoro-4-(methylsulfonyl)-, methyl ester; 3-Fluoro-4-(methylsulfonyl)benzoic acid methyl ester; Methyl 3-fluoro-4-methanesulfonylbenzoate; 1215074-49-9; Methyl 3-Fluoro-4-Mesylbenzoate; 4-Methanesulfonyl-3-fluorobenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Fluoro-4-(Methylsulfonyl)Benzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, potency, and impurity profiles. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring material for GLP (Good Laboratory Practice) and cGMP (current Good Manufacturing Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.