Description

3-(Difluoromethoxy)-2,6-Difluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity imparted by the difluoromethoxy and difluoro substitutions, enabling precise molecular modifications. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of new drugs targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Material Precursor: Serves as a starting material for synthesizing fluorinated liquid crystals used in high-performance displays.
• Organic Electronics: Employed in the development of novel organic semiconductors and electron-transport materials due to its electron-withdrawing properties.
• Chemical Research & Development: A versatile reagent for introducing the difluoromethoxy group into complex molecules in academic and industrial research settings.
• Fluorinated Polymer Modification: Acts as a monomer or modifier to impart specific properties like chemical resistance or low surface energy to specialty polymers.

Basic Information

Product Name	3-(Difluoromethoxy)-2,6-Difluorobenzoic Acid
CAS No.	1214379-50-6
Molecular Formula	C8H4F4O3
Molecular Weight	224.11 g/mol
Synonyms	2,6-Difluoro-3-(difluoromethoxy)benzoic Acid; Benzoic acid, 2,6-difluoro-3-(difluoromethoxy)-; 3-(Difluoromethoxy)-2,6-difluorobenzoic acid; 2,6-Difluoro-α,α,α-trifluoro-m-cresotate (related); DFMOBA (abbreviation)
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethoxy)-2,6-Difluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets exacting standards for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and stored under an inert atmosphere or with appropriate desiccants to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.