Description

Ethyl 2-Fluoro-3-Nitrobenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those containing fluorinated aromatic systems for improved metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atom and nitro group confer specific biological activity.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated aromatic cores used in electronic and optoelectronic materials.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, ester hydrolysis, and nitro group reduction to access a variety of substituted benzoic acid derivatives.
• Dye & Pigment Intermediate: Employed in the production of specialized fluorinated dyes and colorants.

Basic Information

Product Name	Ethyl 2-Fluoro-3-Nitrobenzoate
CAS No.	1214379-18-6
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Benzoic acid, 2-fluoro-3-nitro-, ethyl ester; Ethyl 2-fluoro-3-nitrobenzoate; 2-Fluoro-3-nitrobenzoic acid ethyl ester; Ethyl o-fluoro-m-nitrobenzoate; 1214379-18-6; Ethyl 2-fluoro-3-nitrobenzoate (CAS 1214379-18-6)
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-3-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.