Description

2-Nitro-5-(Trifluoromethyl)Benzoic Acid is a high-purity, multi-functional aromatic building block characterized by its nitro and trifluoromethyl substituents. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting specific receptors or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the nitro and trifluoromethyl groups contribute to biological activity and environmental persistence profiles.
• Material Science Research: Serves as a precursor for functionalized monomers or ligands in the development of advanced polymers, liquid crystals, or metal-organic frameworks (MOFs).
• Organic Synthesis & Chemical Research: Employed in academic and industrial laboratories for exploring new synthetic methodologies, such as cross-coupling reactions or nucleophilic aromatic substitutions, due to its reactive handles.
• Dye & Pigment Intermediate: Acts as a starting material for the synthesis of specialized dyes and pigments, where the electron-withdrawing groups influence color and fastness properties.

Basic Information

Product Name	2-Nitro-5-(Trifluoromethyl)Benzoic Acid
CAS No.	1214373-54-2
Molecular Formula	C8H4F3NO4
Molecular Weight	235.12 g/mol
Synonyms	5-(Trifluoromethyl)-2-nitrobenzoic acid; 2-Nitro-5-(trifluoromethyl)benzoic acid; Benzoic acid, 2-nitro-5-(trifluoromethyl)-; 2-Nitro-alpha,alpha,α-trifluoro-p-toluic acid
EINECS	Contact for details

Quality Control

Our 2-Nitro-5-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.