Description

Ethyl 2-Bromo-5-(Trifluoromethyl)Benzoate is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its unique structure, featuring both bromo and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organocatalysts used in cross-coupling reactions and asymmetric synthesis.
• Material Science: Employed in the research and development of advanced organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing characteristics.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Ethyl 2-Bromo-5-(Trifluoromethyl)Benzoate
CAS No.	1214336-55-6
Molecular Formula	C10H8BrF3O2
Molecular Weight	297.07 g/mol
Synonyms	Ethyl 2-Bromo-α,α,α-trifluoro-m-toluate; Benzoic acid, 2-bromo-5-(trifluoromethyl)-, ethyl ester; 2-Bromo-5-(trifluoromethyl)benzoic Acid Ethyl Ester; Ethyl 2-Bromo-5-(trifluoromethyl)benzoate; Ethyl 2-Bromo-α,α,α-trifluoro-m-toluate; m-Toluic acid, 2-bromo-α,α,α-trifluoro-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-Bromo-5-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed control of related substances. A comprehensive Certificate of Analysis (COA) is provided with each shipment, documenting identity, assay, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.