Description

Methyl 4-Chloro-2,3-Difluorobenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for modulating biological activity and metabolic stability. It is essential for research chemists and process development scientists working on novel active ingredients, including pharmaceuticals, crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those containing a difluorobenzene core, used in drug discovery and development.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the chloro and difluoro substituents contribute to efficacy and selectivity.
• Liquid Crystal & OLED Materials: Used in the research and production of fluorinated organic electronic materials for displays and lighting applications.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and ester transformations to construct more complex aromatic systems in academic and industrial R&D.
• Polymer Modification: Acts as a monomer or modifier for introducing fluorine-containing aromatic units into specialty polymers to enhance chemical resistance and thermal stability.

Basic Information

Product Name	Methyl 4-Chloro-2,3-Difluorobenzoate
CAS No.	1214334-98-1
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	4-Chloro-2,3-difluorobenzoic acid methyl ester; Methyl 4-chloro-2,3-difluorobenzoate; Benzoic acid, 4-chloro-2,3-difluoro-, methyl ester; 2,3-Difluoro-4-chlorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-2,3-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.