Description

Methyl 2,6-Difluoro-3-Hydroxybenzoate CAS NO 1214332-41-8 is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its unique difluoro-hydroxy substitution pattern makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorine and hydroxyl functional groups into polymer chains, enhancing material properties like chemical resistance and surface energy.
• Organic Synthesis Reagent: A versatile synthon in cross-coupling reactions, esterifications, and nucleophilic aromatic substitutions for academic and industrial R&D.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments that offer improved lightfastness and color properties.

Basic Information

Product Name	Methyl 2,6-Difluoro-3-Hydroxybenzoate
CAS No.	1214332-41-8
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	2,6-Difluoro-3-hydroxybenzoic acid methyl ester; Methyl 2,6-difluoro-3-hydroxybenzoate; 3-Hydroxy-2,6-difluorobenzoic acid methyl ester; Benzoic acid, 2,6-difluoro-3-hydroxy-, methyl ester; Methyl 3-hydroxy-2,6-difluorobenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2,6-Difluoro-3-Hydroxybenzoate adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing comprehensive specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.