Description

3-(4-Fluorophenyl)-5-Fluorobenzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its difluorinated biphenyl-like structure imparts desirable metabolic stability and bioavailability. It is primarily sought by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine atoms for improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Acts as a monomer or modifier for creating high-performance, fluorinated polymers with unique chemical resistance and thermal stability.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for OLED devices.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	3-(4-Fluorophenyl)-5-Fluorobenzoic Acid
CAS No.	1214330-80-9
Molecular Formula	C13H8F2O2
Molecular Weight	234.20 g/mol
Synonyms	5-Fluoro-3-(4-fluorophenyl)benzoic Acid; 3-(4-Fluorophenyl)-5-fluorobenzoic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-3'-fluoro-; 4-Fluoro-3'-(fluorobiphenyl)-3-carboxylic Acid; 3'-Fluoro-4-fluorobiphenyl-3-carboxylic Acid; 3-(4-Fluorophenyl)-5-fluorobenzoate; 1214330-80-9
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.