Description

(S)-3,3,3-Trifluoro-1-Phenyl-Propylamine is a high-value, chiral amine building block characterized by its trifluoromethyl group and phenyl substituent. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its specific stereochemistry and fluorine atoms impart desirable metabolic stability and bioavailability. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with unique surface properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorination on molecular properties.

Basic Information

Product Name	(S)-3,3,3-Trifluoro-1-Phenyl-Propylamine
CAS No.	1213582-26-3
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	(S)-1-Phenyl-3,3,3-trifluoropropan-1-amine; (S)-α-Methyl-3,3,3-trifluorophenethylamine; (S)-3,3,3-Trifluoro-1-phenylethylamine; (S)-1-(3,3,3-Trifluoropropyl)benzeneamine; (S)-TFPA; (S)-Trifluorophenpropylamine
EINECS	Contact for details

Quality Control

Our (S)-3,3,3-Trifluoro-1-Phenyl-Propylamine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.