Description

2-((1S)-1-Aminoethyl)-5-Methylphenol is a chiral, optically active phenolic amine derivative of significant interest in advanced organic synthesis. This compound matters as a key chiral building block and intermediate for the development of enantiomerically pure pharmaceuticals and fine chemicals. Industries that need it include pharmaceutical R&D, where it is utilized in the synthesis of active pharmaceutical ingredients (APIs), and specialty chemical manufacturing for producing high-value agrochemicals and catalysts.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enabling highly selective chemical transformations in fine chemical production.
• Agrochemical Research: Serves as a building block for developing novel, optically active pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Employed in the synthesis of specialty polymers and advanced materials where the chiral center imparts specific optical or mechanical properties.
• Bioconjugation Chemistry: Utilized for modifying biomolecules or surfaces due to its reactive amine and phenolic functional groups.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-((1S)-1-Aminoethyl)-5-Methylphenol
CAS No.	1213532-58-1
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	(S)-1-(3-Hydroxy-4-methylphenyl)ethan-1-amine; (S)-2-(1-Aminoethyl)-5-methylphenol; (1S)-1-(3-Hydroxy-4-methylphenyl)ethylamine; 5-Methyl-2-[(1S)-1-aminoethyl]phenol; L-2-(1-Aminoethyl)-5-methylphenol; (S)-α-Methyl-4-methyl-m-aminophenol; 2-[(S)-1-Aminoethyl]-5-methylphenol
EINECS	Contact for details

Quality Control

Our 2-((1S)-1-Aminoethyl)-5-Methylphenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.