Description

(S)-Cyclopropyl(Thiophen-3-Yl)Methanamine CAS NO 1213206-69-9 is a high-purity chiral amine building block featuring a cyclopropyl and a thiophene moiety. This compound is of significant value in medicinal chemistry and pharmaceutical research as a key intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with improved efficacy and pharmacokinetic profiles.
• Agrochemical Development: Serves as a precursor in the research and development of new pesticides and herbicides with novel modes of action.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis, enhancing the stereoselectivity of synthetic transformations.
• Fine Chemical Synthesis: A versatile intermediate for constructing complex molecules in custom synthesis and contract manufacturing projects.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(S)-Cyclopropyl(Thiophen-3-Yl)Methanamine
CAS No.	1213206-69-9
Molecular Formula	C8H11NS
Molecular Weight	153.24 g/mol
Synonyms	(S)-1-Cyclopropyl-1-(thiophen-3-yl)methanamine; (S)-Cyclopropyl(thiophen-3-yl)methylamine; (S)-α-Cyclopropyl-3-thiophenemethylamine; (S)-3-Thienyl(cyclopropyl)methylamine; (S)-Aminomethyl(cyclopropyl)(3-thienyl)methane; (1S)-1-Cyclopropyl-1-(3-thienyl)methanamine; (S)-Cyclopropyl-3-thienylmethylamine; (S)-CPTM
EINECS	Contact for details

Quality Control

Our (S)-Cyclopropyl(Thiophen-3-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.