Description

(R)-1-(3-Chlorophenyl)-2-Methylpropan-1-Amine CAS NO 1212064-17-9 is a chiral amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals. Pharmaceutical R&D teams and fine chemical manufacturers need it to construct complex molecules with specific stereochemistry, enabling the production of more effective and targeted therapeutics.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block in the synthesis of advanced, chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands for metal-catalyzed reactions, such as hydrogenation and cross-coupling.
• Material Science: Potential precursor for specialty polymers and advanced organic materials requiring specific molecular architectures.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development within contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	(R)-1-(3-Chlorophenyl)-2-Methylpropan-1-Amine
CAS No.	1212064-17-9
Molecular Formula	C10H14ClN
Molecular Weight	183.68 g/mol
Synonyms	(R)-1-(3-Chlorophenyl)-2-methylpropan-1-amine; (R)-3-Chloro-α-isobutylbenzylamine; (R)-1-Amino-1-(3-chlorophenyl)-2-methylpropane; (R)-1-(3-Chlorophenyl)-2-methyl-1-propanamine; (R)-3-Chloro-α-isobutylbenzylamine; (R)-1-(3-Chloro-phenyl)-2-methyl-propylamine; (R)-3-Chloro-α-isobutyl-benzylamine; (R)-1-(m-Chlorophenyl)-2-methylpropylamine
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Chlorophenyl)-2-Methylpropan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.