Description

5-Methyl-3-(trifluoromethyl)picolinic acid is a high-value, multi-functional heterocyclic building block characterized by its picolinic acid core substituted with methyl and trifluoromethyl groups. This compound is essential for its role in facilitating structure-activity relationship (SAR) studies and enabling the synthesis of novel molecules with enhanced properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Ligand for Catalysis: Used in the preparation of specialized ligands for transition metal catalysts in cross-coupling and other synthetic transformations.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, functionalized structure.
• Chemical Biology Probe: Utilized as a molecular scaffold for developing probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	5-Methyl-3-(trifluoromethyl)picolinic Acid
CAS No.	1211535-31-7
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	5-Methyl-3-(trifluoromethyl)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 5-methyl-3-(trifluoromethyl)-; 3-Trifluoromethyl-5-methylpicolinic acid; 5-Methyl-3-trifluoromethylpicolinic acid; 1211535-31-7
EINECS	Contact for details

Quality Control

Every batch of 5-Methyl-3-(trifluoromethyl)picolinic acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.