Description

2-Fluoro-6-(Trifluoromethoxy)Benzoic Acid is a high-value fluorinated aromatic building block, distinguished by its unique trifluoromethoxy and fluorine substituents which impart significant electronic and steric properties. This compound is essential for medicinal chemistry and advanced materials research, where its structure is leveraged to modulate lipophilicity, metabolic stability, and binding affinity. It is primarily sought by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine and trifluoromethoxy groups enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving charge transport and thermal stability.
• Polymer Modification: Incorporated as a monomer or additive to engineer specialty polymers with enhanced chemical resistance, low surface energy, or specific optical properties.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reactions in fluorochemistry and as a standard for analytical method development.
• Coordination Chemistry Ligand: The carboxylic acid and fluorine atoms can act as binding sites for metals, useful in catalyst design and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Fluoro-6-(Trifluoromethoxy)Benzoic Acid
CAS No.	1211530-22-1
Molecular Formula	C8H4F4O3
Molecular Weight	224.11 g/mol
Synonyms	2-Fluoro-6-(trifluoromethoxy)benzoic acid; Benzoic acid, 2-fluoro-6-(trifluoromethoxy)-; 6-Fluoro-2-(trifluoromethoxy)benzoic acid; 2-Fluoro-α,α,α-trifluoro-o-anisic acid; 2-Fluoro-6-trifluoromethoxybenzoic acid; 2-Fluoro-6-(trifluoromethoxy)benzenecarboxylic acid; 2-Fluoro-6-(trifluoromethoxy)phenylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain reliability and documentation transparency supports your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.