Description

6-(2,6-Difluorophenyl)-5-Fluoropicolinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific difluorophenyl and fluoropicolinic acid structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing next-generation therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atoms for improved efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists exploring structure-activity relationships (SAR) in new chemical entities.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final steps of API synthesis for targeted therapies.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for catalytic processes in fine chemical production.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory submissions.

Basic Information

Product Name	6-(2,6-Difluorophenyl)-5-Fluoropicolinic Acid
CAS No.	1210419-19-4
Molecular Formula	C₁₂H₆F₃NO₂
Molecular Weight	265.18 g/mol
Synonyms	5-Fluoro-6-(2,6-difluorophenyl)picolinic acid; 6-(2,6-Difluorophenyl)-5-fluoropyridine-2-carboxylic acid; 2,6-Difluoro-5-fluoropicolinic acid derivative; DFPA Intermediate; CAS 1210419-19-4; 5-Fluoro-6-(2,6-difluorophenyl)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-(2,6-Difluorophenyl)-5-Fluoropicolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.