Description

tert-Butyl (R)-4-(1-Hydroxyethyl)Piperidine-1-Carboxylate is a high-purity chiral piperidine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a stereochemically defined building block for constructing complex molecules with high enantiomeric purity. This compound is essential for research and development teams in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Asymmetric Catalysis: Employed as a precursor for chiral ligands or catalysts in stereoselective transformations.
• Chemical Research: A versatile building block for academic and industrial research in medicinal chemistry and organic synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	tert-Butyl (R)-4-(1-Hydroxyethyl)Piperidine-1-Carboxylate
CAS No.	1206830-71-8
Molecular Formula	C12H23NO3
Molecular Weight	229.32 g/mol
Synonyms	(R)-1-Boc-4-(1-Hydroxyethyl)piperidine; (R)-tert-Butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 4-(1-hydroxyethyl)-, 1,1-dimethylethyl ester, (4R)-; 1,1-Dimethylethyl (4R)-4-(1-hydroxyethyl)-1-piperidinecarboxylate; (R)-4-(1-Hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl (R)-(-)-4-(1-Hydroxyethyl)piperidine-1-carboxylate; BOC-(R)-4-(1-Hydroxyethyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl (R)-4-(1-Hydroxyethyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.