Description

5-Fluoro-2,3-Dihydrobenzofuran-7-Carboxylic Acid is a high-purity fluorinated benzofuran derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex, functionalized heterocyclic scaffolds. Pharmaceutical R&D and fine chemical manufacturers need it to create next-generation drug candidates with enhanced metabolic stability and target specificity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in the research and production of advanced herbicides and fungicides with fluorinated active ingredients.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the creation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and novel fluorination methodologies.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	5-Fluoro-2,3-Dihydrobenzofuran-7-Carboxylic Acid
CAS No.	1197231-40-5
Molecular Formula	C9H7FO3
Molecular Weight	182.15 g/mol
Synonyms	7-Carboxy-5-fluoro-2,3-dihydrobenzofuran; 5-Fluoro-2,3-dihydro-7-benzofurancarboxylic Acid; 5-Fluoro-7-carboxy-2,3-dihydrobenzofuran; 1197231-40-5; 5-Fluoro-2,3-dihydro-1-benzofuran-7-carboxylic acid; 5-Fluoro-7-benzofurancarboxylic acid, 2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2,3-Dihydrobenzofuran-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.