Description

cis-5,8,11,14,17-Eicosapentaenoic Acid-[19,19,20,20,20-D5] is a high-purity, stable isotope-labeled analog of eicosapentaenoic acid (EPA), a critical ω-3 fatty acid. This deuterated compound is essential for advanced analytical and metabolic research, providing an internal standard for precise quantification and tracer studies. It is primarily used by researchers and manufacturers in pharmaceutical development, nutritional science, and clinical diagnostics to ensure accuracy and reliability in complex biological assays.

Application

• Internal Standard for Mass Spectrometry (LC-MS/MS, GC-MS): Enables accurate quantification of endogenous EPA in biological matrices like plasma, serum, and tissues.
• Metabolic Tracer Studies: Used to investigate the absorption, distribution, metabolism, and excretion (ADME) pathways of ω-3 fatty acids in vivo.
• Pharmaceutical R&D: Supports the development and bioanalysis of ω-3-based drugs and high-purity formulations.
• Clinical Research & Diagnostics: Facilitates precise measurement of fatty acid profiles for studies on cardiovascular health, inflammation, and neurological disorders.
• Nutraceutical & Dietary Supplement Analysis: Ensures label claim verification and quality control in ω-3 product manufacturing.
• Biomarker Discovery & Validation: Aids in the identification and validation of lipid-based biomarkers for various disease states.

Basic Information

Product Name	cis-5,8,11,14,17-Eicosapentaenoic Acid-[19,19,20,20,20-D5]
CAS No.	1197205-73-4
Molecular Formula	C₂₀H₂₅D₅O₂
Molecular Weight	307.5 g/mol (approx.)
Synonyms	EPA-d5; [19,19,20,20,20-D5]-Eicosapentaenoic Acid; Deuterated Eicosapentaenoic Acid; (5Z,8Z,11Z,14Z,17Z)-Icosa-5,8,11,14,17-pentaenoic-19,19,20,20,20-d5 acid; 5,8,11,14,17-EPA-d5; cis-5,8,11,14,17-EPA-d5; D5-Eicosapentaenoic Acid; ω-3 Fatty Acid-d5
EINECS	Contact for details

Quality Control

Our isotope-labeled compounds are manufactured under strict quality systems to ensure the highest chemical purity and isotopic enrichment. Each batch is analyzed using advanced techniques including NMR and mass spectrometry to confirm structural integrity and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity, and analytical methods is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98% (area)
Isotopic Purity (MS)	≥ 98 atom % D
Chemical Purity (GC)	≥ 95%
Solubility	Soluble in ethanol, DMSO, chloroform

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.