Description

4-(2-Fluorophenyl)-3-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique difluorinated biphenyl-like structure, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by pharmaceutical R&D and agrochemical manufacturers for the development of new active ingredients, particularly where enhanced metabolic stability and bioavailability are required.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atoms contribute to improved lipophilicity and target binding.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance display technologies.
• Polymer Chemistry: Acts as a monomer or modifier for synthesizing specialty polymers with enhanced chemical resistance and thermal stability.
• Organic Electronics: Employed in the synthesis of charge-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl structures in medicinal chemistry.

Basic Information

Item	Details
Product Name	4-(2-Fluorophenyl)-3-Fluorobenzoic Acid
CAS No.	1192548-50-7
Molecular Formula	C13H8F2O2
Molecular Weight	234.20 g/mol
Synonyms	3-Fluoro-4-(2-fluorophenyl)benzoic Acid; 2'-Fluoro-3-fluoro[1,1'-biphenyl]-4-carboxylic Acid; 4-(2-Fluorophenyl)-3-fluorobenzoic Acid; [1,1'-Biphenyl]-4-carboxylic acid, 2',3-difluoro-; 2',3-Difluorobiphenyl-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of 4-(2-Fluorophenyl)-3-Fluorobenzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.