Description

2-Fluoro-4-Methoxynicotinic Acid is a high-value fluorinated nicotinic acid derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and methoxy substituents, provides essential electronic and steric properties for designing novel active compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of advanced molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Acts as a precursor for functionalized heterocyclic compounds used in organic electronic materials.
• Chemical Biology Probes: Utilized to synthesize fluorinated analogs of natural products for mechanism-of-action studies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Fluoro-4-Methoxynicotinic Acid
CAS No.	1190315-81-1
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	4-Methoxy-2-fluoronicotinic acid; 2-Fluoro-4-methoxypyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-fluoro-4-methoxy-; 2-Fluoro-4-methoxy-3-pyridinecarboxylic acid; 2-Fluoro-4-methoxypyridine-3-carboxylic acid; 2-Fluoro-4-methoxy-3-carboxypyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methoxynicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.