Description

5-(4-Benzyloxyphenyl)-[4,5-Di-13C,3-15N]-2-Oxazolidone is a stable isotope-labeled analog of a key oxazolidinone derivative. This compound is specifically designed for use as an internal standard in quantitative mass spectrometry, providing unmatched accuracy and reliability in analytical measurements. It is essential for researchers and quality control laboratories in the pharmaceutical and agrochemical sectors who require precise quantification of the parent compound in complex matrices such as biological fluids, environmental samples, and drug formulations.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of the non-labeled oxazolidinone in pharmacokinetic and bioanalytical studies.
• Metabolic Pathway Tracing: Used in drug metabolism and disposition (DMPK) studies to track and elucidate metabolic pathways.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradation products during drug development.
• Environmental Fate Studies: Enables precise tracking of agrochemical or pharmaceutical residues in environmental samples.
• Certified Reference Material (CRM): Serves as a high-purity calibrant for method validation and ensuring regulatory compliance (e.g., FDA, EMA).
• Isotope Dilution Mass Spectrometry (IDMS): The gold-standard technique for achieving the highest possible accuracy in quantitative analysis.

Basic Information

Product Name	5-(4-Benzyloxyphenyl)-[4,5-Di-13C,3-15N]-2-Oxazolidone
CAS No.	1190016-97-7
Molecular Formula	C16H1313C215NO3
Molecular Weight	~286.29 g/mol (exact mass varies with isotopic enrichment)
Synonyms	[4,5-Di-13C,3-15N]-5-(4-Benzyloxyphenyl)-2-oxazolidinone; 5-(4-(Benzyloxy)phenyl)-2-oxazolidinone-4,5-13C2,3-15N; 13C2,15N-Labeled 5-(4-Benzyloxyphenyl)-2-oxazolidinone; Isotopically Labeled Oxazolidinone Derivative; Stable Isotope-Labeled Internal Standard (SIL-IS); CAS 1190016-97-7 (unlabeled parent compound analog)
EINECS	Contact for details

Quality Control

Every batch of our stable isotope-labeled materials is produced and analyzed under strict quality management to ensure isotopic and chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % 13C and 15N), chemical purity by HPLC, and identity confirmation by NMR and MS. Our production adheres to cGMP principles where applicable, supporting your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation. Store in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % (at positions 4 & 5)
Isotopic Enrichment (15N)	≥ 99 atom % (at position 3)
Chemical Purity (by 1H NMR)	≥ 97.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.